BMCBI
2011
13 years 7 months ago
2011
Background: Cells coordinate their metabolism, proliferation, and cellular communication according to environmental cues through signal transduction. Because signal transduction h...
BMCBI
2002
13 years 12 months ago
2002
Background: Intracellular signal transduction is achieved by networks of proteins and small molecules that transmit information from the cell surface to the nucleus, where they ul...
IJON
2006
14 years 17 hour ago
2006
We introduce a new approach to model the behavior of neuronal signal transduction networks using stochastic differential equations. We present first a mathematical formulation for...
BMCBI
2006
14 years 2 days ago
2006
Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
BMCBI
2006
14 years 2 days ago
2006
Background: Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an "echo" of real molecular processes in the cell...
BMCBI
2007
14 years 4 days ago
2007
Background: Combinatorial complexity is a challenging problem in detailed and mechanistic mathematical modeling of signal transduction. This subject has been discussed intensively...
BMCBI
2007
14 years 4 days ago
2007
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
APVIS
2009
14 years 1 months ago
2009
In this paper, we propose a stochastic simulation to model and analyze cellular signal transduction. The high number of objects in a simulation requires advanced visualization tec...
CMSB
2009
Springer
14 years 3 months ago
2009
Springer
In this paper we consider the modeling of a selected portion of signal transduction events involved in the angiogenesis process. The detailed model of this process contains a large...
CIS
2004
Springer
14 years 5 months ago
2004
Springer
The pi calculus has been applied to modelling biochemical networks. In these applications, the modelling is done without considerations to exceptions. The Ipi calculus, the Interfe...