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120
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BMCBI
2011
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Artificial Intelligence
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BMCBI 2011
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A theoretical entropy score as a single value to express inhibitor selectivity
14 years 9 months ago
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Background: Designing maximally selective ligands that act on individual targets is the dominant paradigm in drug discovery. Poor selectivity can underlie toxicity and side effect...
Joost C. M. Uitdehaag, Guido J. R. Zaman
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