Sciweavers

JBCB
2007
161views more  JBCB 2007»
13 years 6 months ago
On Cooperative Quasi-Equilibrium Models of transcriptional Regulation
Mechanistic models for transcriptional regulation are derived using the methods of equilibrium statistical mechanics, to model equilibrating processes that occur at a fast time sc...
Eric Mjolsness
BMCBI
2005
145views more  BMCBI 2005»
13 years 6 months ago
CAGER: classification analysis of gene expression regulation using multiple information sources
Background: Many classification approaches have been applied to analyzing transcriptional regulation of gene expressions. These methods build models that can explain a gene's...
Jianhua Ruan, Weixiong Zhang
BMCBI
2007
148views more  BMCBI 2007»
13 years 6 months ago
fREDUCE: Detection of degenerate regulatory elements using correlation with expression
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...
BMCBI
2006
133views more  BMCBI 2006»
13 years 6 months ago
Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae
Background: Signal recognition and information processing is a fundamental cellular function, which in part involves comprehensive transcriptional regulatory (TR) mechanisms carri...
Illés J. Farkas, Chuang Wu, Chakra Chennubh...
BMCBI
2008
98views more  BMCBI 2008»
13 years 6 months ago
GBNet: Deciphering regulatory rules in the co-regulated genes using a Gibbs sampler enhanced Bayesian network approach
Background: Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering ...
Li Shen, Jie Liu, Wei Wang
BMCBI
2010
97views more  BMCBI 2010»
13 years 6 months ago
Dual-functioning transcription factors in the developmental gene network of Drosophila melanogaster
Background: Quantitative models for transcriptional regulation have shown great promise for advancing our understanding of the biological mechanisms underlying gene regulation. Ho...
Denis C. Bauer, Fabian A. Buske, Timothy L. Bailey
RECOMB
2005
Springer
14 years 6 months ago
An Interaction-Dependent Model for Transcription Factor Binding
Transcriptional regulation is accomplished by several transcription factor proteins that bind to specific DNA elements in the relative vicinity of the gene, and interact with each ...
Li-San Wang, Shane T. Jensen, Sridhar Hannenhalli