GEFERENCE: Reference Database for Construing Personal Genome Expression

- With the lowering cost and the increasing discoveries, genomics research filed has materialized personal genome era. Especially, microarray gene expression platform has already made several success stories for prognosis/diagnosis in medical contexts. However, the genome expression profiles, although having extensive information, still not be used in usual clinical context due to its complexity. In this study, we developed a reference database system, GEFERENCE, a searchable space for personal genome expression profiles by reorganizing patient centric genome expression and clinical information extracted from public data repository, GEO. We assembled total 34,745 patient's gene expression data from the 28 different tissue types with corresponding clinical information. And we manually curate the relation of information among individual patient, gene expression data, and clinical information by tight collaboration with clinicians. With GEFERENCE, clinician or medical service provide...

• Type: Conference
• Year: 2009
• Where: BIOCOMP
• Authors: Changwon Keum, Ju Han Kim, Young Soo Song, Kyoung Tai No, Jung Hoon Woo
• Keywords: BIOCOMP 2007, BIOCOMP 2009, Gene Expression, Gene Expression Data, Genome Expression Profiles