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» A comparative study of conservation and variation scores
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BMCBI
2010
94views more  BMCBI 2010»
13 years 5 months ago
A comparative study of conservation and variation scores
Background: Conservation and variation scores are used when evaluating sites in a multiple sequence alignment, in order to identify residues critical for structure or function. A ...
Fredrik Johansson, Hiroyuki Toh
ALMOB
2008
160views more  ALMOB 2008»
13 years 5 months ago
Syntenator: Multiple gene order alignments with a gene-specific scoring function
Background: Identification of homologous regions or conserved syntenies across genomes is one crucial step in comparative genomics. This task is usually performed by genome alignm...
Christian Rödelsperger, Christoph Dieterich
BMCBI
2008
187views more  BMCBI 2008»
13 years 5 months ago
PSAT: A web tool to compare genomic neighborhoods of multiple prokaryotic genomes
Background: The conservation of gene order among prokaryotic genomes can provide valuable insight into gene function, protein interactions, or events by which genomes have evolved...
Christine Fong, Laurence Rohmer, Matthew Radey, Mi...
RECOMB
2005
Springer
14 years 5 months ago
Comparative Systems Biology of the Sporulation Initiation Network in Prokaryotes
Many years of experimental and computational molecular biology of model organisms such as Escherichia coli and Saccharomyces cerevisiae has elucidated the gene regulatory network i...
Michiel J. L. de Hoon, Dennis Vitkup
ISVLSI
2007
IEEE
204views VLSI» more  ISVLSI 2007»
13 years 11 months ago
Designing Memory Subsystems Resilient to Process Variations
As technology scales, more sophisticated fabrication processes cause variations in many different parameters in the device. These variations could severely affect the performance ...
Mahmoud Ben Naser, Yao Guo, Csaba Andras Moritz