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BMCBI
2007
116views more  BMCBI 2007»
13 years 5 months ago
Clustering protein environments for function prediction: finding PROSITE motifs in 3D
Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
Sungroh Yoon, Jessica C. Ebert, Eui-Young Chung, G...
BIBM
2008
IEEE
113views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Towards Site-Based Protein Functional Annotations
Abstract—The exact relationship between protein active centers and protein functions is unclear even after decades of intensive study. To improve the functional prediction abilit...
Seak Fei Lei, Jun Huan
BMCBI
2008
96views more  BMCBI 2008»
13 years 5 months ago
MSDmotif: exploring protein sites and motifs
Background: Protein structures have conserved features
Adel Golovin, Kim Henrick
BMCBI
2007
100views more  BMCBI 2007»
13 years 5 months ago
Discovering structural motifs using a structural alphabet: Application to magnesium-binding sites
Background: For many metalloproteins, sequence motifs characteristic of metal-binding sites have not been found or are so short that they would not be expected to be metal-specifi...
Minko Dudev, Carmay Lim
BMCBI
2008
135views more  BMCBI 2008»
13 years 5 months ago
Functional site prediction selects correct protein models
Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...
Vijayalakshmi Chelliah, William R. Taylor