Phylogenetic trees are commonly reconstructed based on hard optimization problems such as Maximum parsimony (MP) and Maximum likelihood (ML). Conventional MP heuristics for produc...
Anupam Bhattacharjee, Kazi Zakia Sultana, Zalia Sh...
Seq7 is a newprogramfor generating multiple structure-based alignments of RNAsequences. Byusing a variant of Dijkstra’s algorithm to find the shortest path through a specially c...
Hidden Markov Models are a widely used generative model for analysing sequence data. A variant, Profile Hidden Markov Models are a special case used in Bioinformatics to represent,...
Stefan Mutter, Bernhard Pfahringer, Geoffrey Holme...
Multiple Sequence Alignment (MSA) is one of the most fundamental problems in computational molecular biology. The running time of the best known scheme for finding an optimal ali...
Background: The development, in the last decade, of stochastic heuristics implemented in robust application softwares has made large phylogeny inference a key step in most compara...