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» Improving the Quality of Automatic DNA Sequence Assembly Usi...
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ISMB
1996
13 years 6 months ago
Improving the Quality of Automatic DNA Sequence Assembly Using Fluorescent Trace-Data Classifications
Virtually all large-scale sequencing projects use automatic sequence-assembly programs to aid in the determination of DNA sequences. The computer-generated assemblies require subs...
Carolyn F. Allex, Schuyler F. Baldwin, Jude W. Sha...
ISMB
1997
13 years 6 months ago
Increasing Consensus Accuracy in DNA Fragment Assemblies by Incorporating Fluorescent Trace Representations
We present a new method for determining the consensus sequence in DNA fragment assemblies. The new method, Trace-Evidence, directly incorporates aligned ABI trace information into...
Carolyn F. Allex, Schuyler F. Baldwin, Jude W. Sha...
BMCBI
2010
133views more  BMCBI 2010»
13 years 4 months ago
Improving de novo sequence assembly using machine learning and comparative genomics for overlap correction
Background: With the rapid expansion of DNA sequencing databases, it is now feasible to identify relevant information from prior sequencing projects and completed genomes and appl...
Lance E. Palmer, Mathäus Dejori, Randall A. B...
FUZZIEEE
2007
IEEE
13 years 11 months ago
Decoding Trace Peak Behaviour - A Neuro-Fuzzy Approach
— DNA sequence basecalling is commonly regarded as a solved problem, despite significant error rates being reflected in inaccuracies in databases and genome annotations. This has...
David Thornley, Stavros Petridis