Sciweavers

ISMB
1993
13 years 6 months ago
The Induction of Rules for Predicting Chemical Carcinogenesis in Rodents
This paper presents results from an ongoing effort in applying a variety of induction-based methods to the problem of predicting the biological activity of noncongeneric (structu...
Dennis Bahler, Douglas W. Bristol
ISMB
1993
13 years 6 months ago
Using Dirichlet Mixture Priors to Derive Hidden Markov Models for Protein Families
A Bayesian method for estimating the amino acid distributions in the states of a hidden Markov model (HMM) for a protein familyor the columns of a multiple alignment of that famil...
Michael Brown, Richard Hughey, Anders Krogh, I. Sa...
ISMB
1993
13 years 6 months ago
Probabilistic Structure Calculations: A Three-Dimensional tRNA Structure from Sequence Correlation Data
Algorithmsbasedonprobability theorycanaddressissues of uncertainty directly throughtheir representational frameworkandtheir theoryfor data combination.In this paper, wediscuss the...
Russ B. Altman
ISMB
1993
13 years 6 months ago
Knowledge Discovery in GENBANK
Wedescribe various methods designed to discover knowledge in the GenBanknucleic acid sequence database. Using a grammatical model of gene structure, we create a parse tree of a ge...
Jeffery S. Aaronson, Juergen Haas, G. Christian Ov...
ISMB
1993
13 years 6 months ago
Representation for Discovery of Protein Motifs
There are several dimensions and levels of complexity in which information on protein motifs may be available. For example, onedimensional sequence motifs may be associated with s...
Darrell Conklin, Suzanne Fortier, Janice I. Glasgo...
ISMB
1993
13 years 6 months ago
Knowledge-Based Generation of Machine-Learning Experiments: Learning with DNA Crystallography Data
Thoughit has been possible in the past to learn to predict DNAhydration patterns from crystallographic data, there is ambiguity in the choice of training data (both in terms of th...
Dawn M. Cohen, Casimir A. Kulikowski, Helen Berman
ISMB
1993
13 years 6 months ago
Protein Topology Prediction through Parallel Constraint Logic Programming
Dominic A. Clark, Christopher J. Rawlings, Jack Sh...
ISMB
1994
13 years 6 months ago
An Improved System for Exon Recognition and Gene Modeling in Human DNA Sequence
A new version of the GRAIL system (Uberbacher and Mural, 1991; Mural et al., 1992; Uberbacher et al., 1993), called GRAILII, has recently been developed (Xu et al., 1994). GRAILII...
Yin Xu, J. Ralph Einstein, Richard J. Mural, Manes...
ISMB
1994
13 years 6 months ago
Optimally Parsing a Sequence into Different Classes Based on Multiple Types of Evidence
Weconsider the problem of parsing a sequence into different classes of subsequences.Twocommonexamplesare finding the exons and introns in genomicsequences and identifying the seco...
Gary D. Stormo, David Haussler
ISMB
1994
13 years 6 months ago
GeneQuiz: A Workbench for Sequence Analysis
Wepresent the prototype of a software system, cMledGeneQuiz,for large-scale biological sequence analysis. The system was designed to meet the needs that arise in computational seq...
Michael Scharf, Reinhard Schneider, Georg Casari, ...