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ISMB
1994
13 years 6 months ago
Evolution of a Computer Program for Classifying Protein Segments as Transmembrane Domains Using Genetic Programming
The recently-developedgenetic programming paradigmisused to evoIve a computer program to classify a given protein segment as being a transmembrane domainor non-uansmembranearea of...
John R. Koza
ISMB
1994
13 years 6 months ago
Discovering Side-Chain Correlations In alpha-Helices
Tod M. Klingler, Douglas L. Brutlag
ISMB
1994
13 years 6 months ago
Toward Unification of Taxonomy Databases in a Distributed Environment
Hajime Kitakami, Yoshio Tateno, Takashi Gojobori
ISMB
1994
13 years 6 months ago
Inductive Logic Programming Used to Discover Topological Constraints in Protein Structures
Thispaperdescribesthe applicationof the Inductive Logic Programming0LP) program GOLEMto the discoveryof constraintsin the packingof beta-sheets in alpha/betaproteins. Theseconstra...
Ross D. King, Dominic A. Clark, Jack Shirazi, Mich...
ISMB
1994
13 years 6 months ago
An Efficient Method for Multiple Sequence Alignment
Multiple sequence alignment has been a useful methodin the study of molecular evolution and sequence-structure relationships. This paper presents a newmethodfor multiple sequence ...
Jin Kim, Sakti Pramanik
ISMB
1994
13 years 6 months ago
Representations of Metabolic Knowledge: Pathways
The automatic generation of drawings of metabolic pathways is a challenging problem that depends intimately on exactly what information has been recorded for each pathway, and on ...
Peter D. Karp, Suzanne M. Paley
ISMB
1994
13 years 6 months ago
Stochastic Motif Extraction Using Hidden Markov Model
In this paper, westudy the application of an ttMM(hidden Markov model) to the problem of representing protein sequencesby a stochastic motif. Astochastic protein motif represents ...
Yukiko Fujiwara, Minoru Asogawa, Akihiko Konagaya
ISMB
1994
13 years 6 months ago
Neural Networks for Determining Protein Specificity and Multiple Alignment of Binding Sites
Weuse a quantitative definition of specificity to developa neural networkfor the identification of commonprotein binding sites in a collection of unaligned DNAfragments. Wedemonst...
John M. Heumann, Alan S. Lapedes, Gary D. Stormo