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ISMB
1994
13 years 6 months ago
Knowledge Discovery of Multilevel Protein Motifs
A new category of protein motif is introduced. This type of motif captures, in addition to global structure, the nested structure of its componentparts. Adata.set of four proteins...
Darrell Conklin, Suzanne Fortier, Janice I. Glasgo...
ISMB
1994
13 years 6 months ago
VQLM: A Visual Query Language for Macromolecular Structural Databases
Dawn M. Cohen, Kumar Vadaparty, Bill Dickinson, He...
ISMB
1994
13 years 6 months ago
Genetic Map Construction with Constraints
Apilot program,CME,is describedfor generatinga physical genetic mapfromhybridization fingerprintingdata. CMEis implementedin the parallel constraint logic programming language Eli...
Dominic A. Clark, Christopher J. Rawlings, Sylvie ...
ISMB
1996
13 years 6 months ago
Gene Recognition in Cyanobacterium Genomic Sequence Data Using the Hidden Markov Model
We have developed a hidden Markov model (HMM)to detect the protein coding regions within one megabase contiguous sequence data, registered in a database called GenBankin eight ent...
Tetsushi Yada, Makoto Hirosawa
ISMB
1996
13 years 6 months ago
A Knowledge-Based Method for Protein Structure Refinement and Prediction
The native conformation of a protein, in a given environment, is determined entirely by the various interatomic interactions dictated by the amino acid sequence (1-3). We describe...
Shankar Subramaniam, David K. Tcheng, James M. Fen...
ISMB
1996
13 years 6 months ago
Finding Genes in DNA Using Decision Trees and Dynamic Programming
This study demonstratesthe use of decision tree classifiers as the basis for a general gene-finding system. The system uses a dynamic programmingalgorithm that. finds the optimal ...
Steven Salzberg, Xin Chen, John Henderson, Kenneth...
ISMB
1996
13 years 6 months ago
Compact Encoding Strategies for DNA Sequence Similarity Search
Determining whether two DNA sequences are similar is an essential component of DNA sequence analysis. Dynamic programming is the algorithm of choice if computational time is not t...
David J. States, Pankaj Agarwal
ISMB
1996
13 years 6 months ago
Refining Neural Network Predictions for Helical Transmembrane Proteins by Dynamic Programming
For transmembrane proteins experimental determina-tion of three-dimensional structure is problematic. However, membrane proteins have important impact for molecular biology in gen...
Burkhard Rost, Rita Casadio, Piero Fariselli