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BIBE
2007
IEEE
195views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Finding Clusters of Positive and Negative Coregulated Genes in Gene Expression Data
— In this paper, we propose a system for finding partial positive and negative coregulated gene clusters in microarray data. Genes are clustered together if they show the same p...
Kerstin Koch, Stefan Schönauer, Ivy Jansen, J...
BIBE
2007
IEEE
147views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
A New Alignment-Independent Algorithm for Clustering Protein Sequences
—The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important, the challenge is to identify subfamilies of evolut...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski
BIBE
2007
IEEE
125views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Large-scale Discovery of Regulatory Motifs Involved in Alternative Splicing
Alternative splicing is a highly important process in many eukaryotic organisms, but surprisingly little is known about its regulation. Often, this process involves cis-regulatory ...
Sihui Zhao, Jihye Kim, Steffen Heber
BIBE
2007
IEEE
132views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Morphometric Analysis of Hippocampal Shape in Mild Cognitive Impairment: An Imaging Genetics Study
—A computational framework is presented for surface based morphometry to localize shape changes between groups of 3D objects. It employs the spherical harmonic (SPHARM) method fo...
Li Shen, Andrew J. Saykin, Moo K. Chung, Heng Huan...
BIBE
2007
IEEE
176views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
HICCUP: Hierarchical Clustering Based Value Imputation using Heterogeneous Gene Expression Microarray Datasets
Abstract—A novel microarray value imputation method, HICCUP1 , is presented. HICCUP improves upon existing value imputation methods in the several ways. (1) By judiciously integr...
Qiankun Zhao, Prasenjit Mitra, Dongwon Lee, Jaewoo...
BIBE
2007
IEEE
174views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Shortest Path Approaches for the Longest Common Subsequence of a Set of Strings
—We investigate the k-LCS problem that is finding a longest common subsequence (LCS) for k given input strings. The problem is known to have practical solutions for k = 2, but f...
Marina Barsky, Ulrike Stege, Alex Thomo, Chris Upt...
BIBE
2007
IEEE
114views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
A Hierarchical Grow-and-Match Algorithm for Backbone Resonance Assignments Given 3D Structure
Abstract—This paper develops an algorithm for NMR backbone resonance assignment given a 3D structure and a set of relatively sparse 15 N-edited NMR data, with the through-space 1...
Fei Xiong, Chris Bailey-Kellogg
BIBE
2007
IEEE
101views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
A Robotic System for Real-time Tumor Manipulation During Image guided Breast Biopsy
Breast biopsy guided by imaging techniques such as ultrasound is widely used to evaluate suspicious masses within the breast. Currently, ultrasound imaging does not allow live guid...
Vishnu Mallapragada, Nilanjan Sarkar, Tarun Kanti ...
BIBE
2007
IEEE
108views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Using Parsimony to Guide Maximum Likelihood Searches
—The performance of maximum likelihood searches can be boosted by using the most parsimonious tree as a starting point for the search. The time spent in performing the parsimony ...
Kenneth Sundberg, Timothy O'Connor, Hyrum Carroll,...