BMCBI
2006
13 years 5 months ago
2006
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
BMCBI
2006
13 years 5 months ago
2006
Background: Biologists often conduct multiple but different cDNA microarray studies that all target the same biological system or pathway. Within each study, replicate slides with...
BMCBI
2006
13 years 5 months ago
2006
Background: Detecting new coding sequences (CDSs) in viral genomes can be difficult for several reasons. The typically compact genomes often contain a number of overlapping coding...
BMCBI
2006
13 years 5 months ago
2006
Background: Large-scale genetic mapping projects require data management systems that can handle complex phenotypes and detect and correct high-throughput genotyping errors, yet a...
BMCBI
2006
13 years 5 months ago
2006
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
BMCBI
2006
13 years 5 months ago
2006
BMCBI
2006
13 years 5 months ago
2006
Background: Most virus detection methods are geared towards the detection of specific single viruses or just a few known targets, and lack the capability to uncover the novel viru...
BMCBI
2006
13 years 5 months ago
2006
BMCBI
2006
13 years 5 months ago
2006
Background: The ever-expanding population of gene expression profiles (EPs) from specified cells and tissues under a variety of experimental conditions is an important but difficu...
BMCBI
2006
13 years 5 months ago
2006
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...