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BMCBI
2010
154views more  BMCBI 2010»
13 years 5 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
BMCBI
2010
175views more  BMCBI 2010»
13 years 5 months ago
Saliva Ontology: An ontology-based framework for a Salivaomics Knowledge Base
Background: The Salivaomics Knowledge Base (SKB) is designed to serve as a computational infrastructure that can permit global exploration and utilization of data and information ...
Jiye Ai, Barry Smith, Wong T. David
BMCBI
2010
128views more  BMCBI 2010»
13 years 5 months ago
MPprimer: a program for reliable multiplex PCR primer design
Background: Multiplex PCR, defined as the simultaneous amplification of multiple regions of a DNA template or multiple DNA templates using more than one primer set (comprising a f...
Zhiyong Shen, Wubin Qu, Wen Wang, Yiming Lu, Yongh...
BMCBI
2010
116views more  BMCBI 2010»
13 years 5 months ago
permGPU: Using graphics processing units in RNA microarray association studies
Background: Many analyses of microarray association studies involve permutation, bootstrap resampling and crossvalidation, that are ideally formulated as embarrassingly parallel c...
Ivo D. Shterev, Sin-Ho Jung, Stephen L. George, Ko...
BMCBI
2010
135views more  BMCBI 2010»
13 years 5 months ago
HDAPD: a web tool for searching the disease-associated protein structures
Background: The protein structures of the disease-associated proteins are important for proceeding with the structure-based drug design to against a particular disease. Up until n...
Yi-Ruen Lin, Hsin-Yuan Wei, Tsung-Lin Tsai, Thy-Ho...
BMCBI
2010
150views more  BMCBI 2010»
13 years 5 months ago
AMS 3.0: prediction of post-translational modifications
Background: We present here the recent update of AMS algorithm for identification of post-translational modification (PTM) sites in proteins based only on sequence information, us...
Subhadip Basu, Dariusz Plewczynski
BMCBI
2010
79views more  BMCBI 2010»
13 years 5 months ago
Characterization of phylogenetic networks with NetTest
Miguel Arenas, Mateus Patricio, David Posada, Gabr...
BMCBI
2010
167views more  BMCBI 2010»
13 years 5 months ago
Inference of sparse combinatorial-control networks from gene-expression data: a message passing approach
Background: Transcriptional gene regulation is one of the most important mechanisms in controlling many essential cellular processes, including cell development, cell-cycle contro...
Marc Bailly-Bechet, Alfredo Braunstein, Andrea Pag...
BMCBI
2010
161views more  BMCBI 2010»
13 years 5 months ago
GeneMesh: a web-based microarray analysis tool for relating differentially expressed genes to MeSH terms
Background: An important objective of DNA microarray-based gene expression experimentation is determining interrelationships that exist between differentially expressed genes and ...
Saurin D. Jani, Gary L. Argraves, Jeremy L. Barth,...