BMCBI
2010
13 years 5 months ago
2010
Background: In recent years, gene order data has attracted increasing attention from both biologists and computer scientists as a new type of data for phylogenetic analysis. If ge...
BMCBI
2010
13 years 5 months ago
2010
Background: MicroRNAs (miRNAs) are endogenous small RNAs that play a key role in post-transcriptional regulation of gene expression in animals and plants. The number of known miRN...
BMCBI
2010
13 years 5 months ago
2010
Background: Whole genome association studies using highly dense single nucleotide polymorphisms (SNPs) are a set of methods to identify DNA markers associated with variation in a ...
BMCBI
2010
13 years 5 months ago
2010
Background: Real-time PCR has recently become the technique of choice for absolute and relative nucleic acid quantification. The gold standard quantification method in real-time P...
BMCBI
2010
13 years 5 months ago
2010
Background: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleoti...
BMCBI
2010
13 years 5 months ago
2010
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
BMCBI
2010
13 years 5 months ago
2010
Background: Bisulfite sequencing using next generation sequencers yields genome-wide measurements of DNA methylation at single nucleotide resolution. Traditional aligners are not ...
BMCBI
2010
13 years 5 months ago
2010
Background: The task of recognizing and identifying species names in biomedical literature has recently been regarded as critical for a number of applications in text and data min...
BMCBI
2010
13 years 5 months ago
2010
Background: Previous studies on insect DNA barcoding provide contradictory results and suggest not consistent performances across orders. This work aims at providing a general eva...
BMCBI
2010
13 years 5 months ago
2010
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...