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221views Computer Vision» more  NAR 2011»
11 years 4 months ago
AGRIS: the Arabidopsis Gene Regulatory Information Server, an update
The Arabidopsis Gene Regulatory Information Server (AGRIS; .edu/) provides a comprehensive resource for gene regulatory studies in the model plan...
Alper Yilmaz, Maria Katherine Mejia-Guerra, Kyle K...
11 years 5 months ago
Reconstructing genome-wide regulatory network of E. coli using transcriptome data and predicted transcription factor activities
Background: Gene regulatory networks play essential roles in living organisms to control growth, keep internal metabolism running and respond to external environmental changes. Un...
Yao Fu, Laura R. Jarboe, Julie A. Dickerson
173views more  COMPLEXITY 2010»
11 years 8 months ago
Signal-regulated systems and networks
The paper presents the use of signal regulatory networks, a biologically-inspired model based on gene regulatory networks. Signal regulatory networks are a way of understanding a ...
Terence L. van Zyl, Elizabeth Marie Ehlers
11 years 8 months ago
Inverse perturbation for optimal intervention in gene regulatory networks
Motivation: Analysis and intervention in the dynamics of gene regulatory networks is at the heart of emerging efforts in the development of modern treatment of numerous ailments i...
Nidhal Bouaynaya, Roman Shterenberg, Dan Schonfeld
87views more  CMA 2010»
11 years 11 months ago
A modified uniformization method for the solution of the chemical master equation
The chemical master equation is considered an accurate description of general chemical systems, and especially so for modeling cell cycle and gene regulatory networks. This paper ...
Jingwei Zhang, Layne T. Watson, Yang Cao
11 years 11 months ago
An automatic gene ontology software tool for bicluster and cluster comparisons
We propose an Automatic Gene Ontology (AGO) software as a flexible, open-source Matlab software tool that allows the user to easily compare the results of the bicluster and cluster...
Fadhl M. Al-Akwaa, Yasser M. Kadah
167views Bioinformatics» more  WABI 2010»
11 years 12 months ago
Quantifying the Strength of Natural Selection of a Motif Sequence
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
Chen-Hsiang Yeang
12 years 1 months ago
Bayesian inference for a discretely observed stochastic kinetic model
The ability to infer parameters of gene regulatory networks is emerging as a key problem in systems biology. The biochemical data are intrinsically stochastic and tend to be observ...
Richard J. Boys, Darren J. Wilkinson, Thomas B. L....
12 years 1 months ago
Exploring the Operational Characteristics of Inference Algorithms for Transcriptional Networks by Means of Synthetic Data
The development of structure-learning algorithms for gene regulatory networks depends heavily on the availability of synthetic data sets that contain both the original network and ...
Koenraad Van Leemput, Tim Van den Bulcke, Thomas D...
127views more  DSS 2007»
12 years 1 months ago
Large-scale regulatory network analysis from microarray data: modified Bayesian network learning and association rule mining
We present two algorithms for learning large-scale gene regulatory networks from microarray data: a modified informationtheory-based Bayesian network algorithm and a modified asso...
Zan Huang, Jiexun Li, Hua Su, George S. Watts, Hsi...