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BMCBI
2006
192views more  BMCBI 2006»
10 years 12 months ago
Analysis of circular genome rearrangement by fusions, fissions and block-interchanges
Background: Analysis of genomes evolving via block-interchange events leads to a combinatorial problem of sorting by block-interchanges, which has been studied recently to evaluat...
Chin Lung Lu, Yen-Lin Huang, Tsui Ching Wang, Hsie...
BMCBI
2006
156views more  BMCBI 2006»
10 years 12 months ago
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
Stephan Waack, Oliver Keller, Roman Asper, Thomas ...
BMCBI
2006
99views more  BMCBI 2006»
10 years 12 months ago
Genetic algorithm learning as a robust approach to RNA editing site prediction
Background: RNA editing is one of several post-transcriptional modifications that may contribute to organismal complexity in the face of limited gene complement in a genome. One f...
James Thompson, Shuba Gopal
BMCBI
2006
74views more  BMCBI 2006»
10 years 12 months ago
An unsupervised classification scheme for improving predictions of prokaryotic TIS
Background: Although it is not difficult for state-of-the-art gene finders to identify coding regions in prokaryotic genomes, exact prediction of the corresponding translation ini...
Maike Tech, Peter Meinicke
BMCBI
2006
92views more  BMCBI 2006»
10 years 12 months ago
Similarity-based gene detection: using COGs to find evolutionarily-conserved ORFs
Background: Experimental verification of gene products has not kept pace with the rapid growth of microbial sequence information. However, existing annotations of gene locations c...
Bradford C. Powell, Clyde A. Hutchison III
BMCBI
2006
120views more  BMCBI 2006»
10 years 12 months ago
An improved distance measure between the expression profiles linking co-expression and co-regulation in mouse
Background: Many statistical algorithms combine microarray expression data and genome sequence data to identify transcription factor binding motifs in the low eukaryotic genomes. ...
Ryung S. Kim, Hongkai Ji, Wing Hung Wong
BMCBI
2006
124views more  BMCBI 2006»
10 years 12 months ago
ZCURVE_V: a new self-training system for recognizing protein-coding genes in viral and phage genomes
Background: It necessary to use highly accurate and statistics-based systems for viral and phage genome annotations. The GeneMark systems for gene-finding in virus and phage genom...
Feng-Biao Guo, Chun-Ting Zhang
CORR
2008
Springer
97views Education» more  CORR 2008»
10 years 12 months ago
Posets and Permutations in the Duplication-Loss Model: Minimal Permutations with d Descents
In this paper, we are interested in the combinatorial analysis of the whole genome duplication - random loss model of genome rearrangement initiated in [8] and [7]. In this model,...
Mathilde Bouvel, Elisa Pergola
BMCBI
2008
95views more  BMCBI 2008»
10 years 12 months ago
Universal seeds for cDNA-to-genome comparison
Background: To meet the needs of gene annotation for newly sequenced organisms, optimized spaced seeds can be implemented into cross-species sequence alignment programs to accurat...
Leming Zhou, Jonathan Stanton, Liliana Florea
BMCBI
2008
131views more  BMCBI 2008»
10 years 12 months ago
CoCoNUT: an efficient system for the comparison and analysis of genomes
Background: Comparative genomics is the analysis and comparison of genomes from different species. This area of research is driven by the large number of sequenced genomes and hea...
Mohamed Ibrahim Abouelhoda, Stefan Kurtz, Enno Ohl...
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