Assessing and improving the accuracy of detecting protein adaptation with the TreeSAAP analytical software

The TreeSAAP software has been successfully used in a variety of protein studies for identifying and characterizing adaptation in terms of shifts in the physicochemical properties of amino acid replacements. It differentiates adaptive replacements from those that may have resulted from random mutation. The accuracy of TreeSAAP was tested using simulated protein

• Type: Journal
• Year: 2010
• Where: IJBRA
• Authors: David A. McClellan, David D. Ellison
• Keywords: Acid Replacements, Amino Acid, Amino Acid Exchanges, IJBRA 2010