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BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
13 years 6 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li
BMCBI
2008
144views more  BMCBI 2008»
13 years 6 months ago
WGCNA: an R package for weighted correlation network analysis
Background: Correlation networks are increasingly being used in bioinformatics applications. For example, weighted gene co-expression network analysis is a systems biology method ...
Peter Langfelder, Steve Horvath
BMCBI
2010
133views more  BMCBI 2010»
13 years 6 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
BMCBI
2008
115views more  BMCBI 2008»
13 years 6 months ago
Probe signal correction for differential methylation hybridization experiments
Background: Non-biological signal (or noise) has been the bane of microarray analysis. Hybridization effects related to probe-sequence composition and DNA dye-probe interactions h...
Dustin P. Potter, Pearlly Yan, Tim Hui-Ming Huang,...
CMPB
2010
186views more  CMPB 2010»
13 years 6 months ago
GPU-based cone beam computed tomography
The use of cone beam computed tomography (CBCT) is growing in the clinical arena due to its ability to provide 3-D information during interventions, its high diagnostic quality (su...
Peter B. Noël, Alan M. Walczak, Jinhui Xu, Ja...
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