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BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
14 years 11 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li
BMCBI
2008
144views more  BMCBI 2008»
14 years 11 months ago
WGCNA: an R package for weighted correlation network analysis
Background: Correlation networks are increasingly being used in bioinformatics applications. For example, weighted gene co-expression network analysis is a systems biology method ...
Peter Langfelder, Steve Horvath
BMCBI
2010
133views more  BMCBI 2010»
14 years 11 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
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BMCBI
2008
115views more  BMCBI 2008»
14 years 11 months ago
Probe signal correction for differential methylation hybridization experiments
Background: Non-biological signal (or noise) has been the bane of microarray analysis. Hybridization effects related to probe-sequence composition and DNA dye-probe interactions h...
Dustin P. Potter, Pearlly Yan, Tim Hui-Ming Huang,...
CMPB
2010
186views more  CMPB 2010»
14 years 11 months ago
GPU-based cone beam computed tomography
The use of cone beam computed tomography (CBCT) is growing in the clinical arena due to its ability to provide 3-D information during interventions, its high diagnostic quality (su...
Peter B. Noël, Alan M. Walczak, Jinhui Xu, Ja...
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