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» A Framework for Modeling DNA Based Molecular Systems
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BMCBI
2007
123views more  BMCBI 2007»
14 years 9 months ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
BMCBI
2004
144views more  BMCBI 2004»
14 years 9 months ago
PASBio: predicate-argument structures for event extraction in molecular biology
Background: The exploitation of information extraction (IE), a technology aiming to provide instances of structured representations from free-form text, has been rapidly growing w...
Tuangthong Wattarujeekrit, Parantu K. Shah, Nigel ...
BMCBI
2007
161views more  BMCBI 2007»
14 years 9 months ago
Efficient classification of complete parameter regions based on semidefinite programming
Background: Current approaches to parameter estimation are often inappropriate or inconvenient for the modelling of complex biological systems. For systems described by nonlinear ...
Lars Kuepfer, Uwe Sauer, Pablo A. Parrilo
ISCA
2007
IEEE
196views Hardware» more  ISCA 2007»
15 years 3 months ago
Anton, a special-purpose machine for molecular dynamics simulation
The ability to perform long, accurate molecular dynamics (MD) simulations involving proteins and other biological macromolecules could in principle provide answers to some of the ...
David E. Shaw, Martin M. Deneroff, Ron O. Dror, Je...
BMCBI
2010
129views more  BMCBI 2010»
14 years 9 months ago
Uncovering packaging features of co-regulated modules based on human protein interaction and transcriptional regulatory networks
Background: Network co-regulated modules are believed to have the functionality of packaging multiple biological entities, and can thus be assumed to coordinate many biological fu...
Lina Chen, Hong Wang, Liangcai Zhang, Wan Li, Qian...