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BMCBI
2004
141views more  BMCBI 2004»
15 years 1 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin
115
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IPPS
2007
IEEE
15 years 8 months ago
A Comparative Study of Parallel Metaheuristics for Protein Structure Prediction on the Computational Grid
A comparative study of parallel metaheuristics executed in grid environments is proposed, having as case study a genetic algorithm, a simulated annealing algorithm and a random se...
Alexandru-Adrian Tantar, Nouredine Melab, El-Ghaza...
BMCBI
2008
138views more  BMCBI 2008»
15 years 1 months ago
Using neural networks and evolutionary information in decoy discrimination for protein tertiary structure prediction
Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represent...
Ching-Wai Tan, David T. Jones
APBC
2004
123views Bioinformatics» more  APBC 2004»
15 years 3 months ago
Empirical Knowledge and Genetic Algorithms for Selection of Amide I Frequencies in Protein Secondary Structure Prediction
Here we investigate an extension of a previously suggested "automatic amide I frequency selection procedure" where we introduce an additional criterion utilizing empiric...
Joachim A. Hering, Peter R. Innocent, Parvez I. Ha...
NAR
2006
98views more  NAR 2006»
15 years 1 months ago
dbPTM: an information repository of protein post-translational modification
ACT dbPTM is a database that compiles information on protein post-translational modifications (PTMs), such as the catalytic sites, solvent accessibility of amino acid residues, pro...
Tzong-Yi Lee, Hsien-Da Huang, Jui-Hung Hung, Hsi-Y...