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CSB
2005
IEEE
160views Bioinformatics» more  CSB 2005»
15 years 7 months ago
Predicting Continuous Epitopes in Proteins
The ability to predict antigenic sites on proteins is crucial for the production of synthetic peptide vaccines and synthetic peptide probes of antibody structure. Large number of ...
Reeti Tandon, Sudeshna Adak, Brion Sarachan, Willi...
BMCBI
2007
109views more  BMCBI 2007»
15 years 1 months ago
A domain-based approach to predict protein-protein interactions
Background: Knowing which proteins exist in a certain organism or cell type and how these proteins interact with each other are necessary for the understanding of biological proce...
Mudita Singhal, Haluk Resat
BMCBI
2005
97views more  BMCBI 2005»
15 years 1 months ago
Sequence variation in ligand binding sites in proteins
Background: The recent explosion in the availability of complete genome sequences has led to the cataloging of tens of thousands of new proteins and putative proteins. Many of the...
Thomas J. Magliery, Lynne Regan
BMCBI
2006
130views more  BMCBI 2006»
15 years 1 months ago
Docking protein domains in contact space
Background: Many biological processes involve the physical interaction between protein domains. Understanding these functional associations requires knowledge of the molecular str...
Stefano Lise, Alice Walker-Taylor, David T. Jones
BMCBI
2010
116views more  BMCBI 2010»
15 years 1 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...