Sciweavers

385 search results - page 57 / 77
» A Knowledge-Based Method for Protein Structure Refinement an...
Sort
View
BMCBI
2007
129views more  BMCBI 2007»
14 years 12 months ago
Exploring inconsistencies in genome-wide protein function annotations: a machine learning approach
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
Carson M. Andorf, Drena Dobbs, Vasant Honavar
ALMOB
2006
155views more  ALMOB 2006»
14 years 11 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
BMCBI
2007
117views more  BMCBI 2007»
14 years 12 months ago
Supervised multivariate analysis of sequence groups to identify specificity determining residues
Background: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper ...
Iain M. Wallace, Desmond G. Higgins
BIBM
2007
IEEE
104views Bioinformatics» more  BIBM 2007»
15 years 3 months ago
A Protocol to Detect Local Affinities Involved in Proteins Distant Interactions
The tridimensional structure of a protein is constrained or stabilized by some local interactions between distant residues of the protein, such as disulfide bonds, electrostatic i...
Christophe Nicolas Magnan, Cécile Capponi, ...
AI
2003
Springer
15 years 5 months ago
An Improved Ant Colony Optimisation Algorithm for the 2D HP Protein Folding Problem
The prediction of a protein’s structure from its amino-acid sequence is one of the most important problems in computational biology. In the current focus on a widely studied abst...
Alena Shmygelska, Holger H. Hoos