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» A Method for Similarity-Based Grouping of Biological Data
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BMCBI
2010
72views more  BMCBI 2010»
14 years 9 months ago
Phylogenetic representativeness: a new method for evaluating taxon sampling in evolutionary studies
Background: Taxon sampling is a major concern in phylogenetic studies. Incomplete, biased, or improper taxon sampling can lead to misleading results in reconstructing evolutionary...
Federico Plazzi, Ronald R. Ferrucci, Marco Passamo...
RECOMB
2002
Springer
15 years 9 months ago
Phase-independent rhythmic analysis of genome-wide expression patterns
We introduce a model-based analysis technique for extracting and characterizing rhythmic expression pro les from genome-wide DNA microarray hybridization data. These patterns are ...
Christopher James Langmead, Anthony K. Yan, C. Rob...
COCOON
2008
Springer
14 years 11 months ago
Quasi-bicliques: Complexity and Binding Pairs
Abstract. Protein-protein interactions (PPIs) are one of the most important mechanisms in cellular processes. To model protein interaction sites, recent studies have suggested to f...
Xiaowen Liu, Jinyan Li, Lusheng Wang
BMCBI
2008
122views more  BMCBI 2008»
14 years 9 months ago
A practical comparison of two K-Means clustering algorithms
Background: Data clustering is a powerful technique for identifying data with similar characteristics, such as genes with similar expression patterns. However, not all implementat...
Gregory A. Wilkin, Xiuzhen Huang
GECCO
2007
Springer
159views Optimization» more  GECCO 2007»
15 years 1 months ago
Discrimination of metabolic flux profiles using a hybrid evolutionary algorithm
Studying metabolic fluxes is a crucial aspect of understanding biological phenotypes. However, it is often not possible to measure these fluxes directly. As an alternative, fluxom...
Stefan Bleuler, Eckart Zitzler