Generalized additive models (GAM) for modelling nonlinear effects of continuous covariates are now well established tools for the applied statistician. In this paper we develop Ba...
Switched dynamical systems have shown great utility in modeling a variety of systems. Unfortunately, the determination of a numerical solution for the optimal control of such syste...
Creating comprehensive simulation models can be expensive and time consuming. This paper discusses our efforts to develop a general methodology that will allow users to quickly an...
Electronic System Level (ESL) design manages the complexity of todays systems by using abstract models. In this context Transaction Level Modeling (TLM) is state-of-theart for desc...
Background: Biological databases and pathway knowledgebases are proliferating rapidly. We are developing software tools for computer-aided hypothesis design and evaluation, and we...