532 search results - page 11 / 107 » A Methodology for Comparative Functional Genomics |
84
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BMCBI
2005
14 years 9 months ago
2005
Background: Expressed Sequence Tags (ESTs) are short and error-prone DNA sequences generated from the 5' and 3' ends of randomly selected cDNA clones. They provide an im...
BMCBI
2005
14 years 9 months ago
2005
Background: Protein function is often dependent on subsets of solvent-exposed residues that may exist in a similar three-dimensional configuration in non homologous proteins thus ...
114
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BMCBI
2011
14 years 1 months ago
2011
Background: Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology. Genome annotations c...
BMCBI
2008
14 years 9 months ago
2008
Background: Data mining in large DNA sequences is a major challenge in microbial genomics and bioinformatics. Oligonucleotide usage (OU) patterns provide a wealth of information f...
121
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BMCBI
2011
14 years 4 months ago
2011
Background: It is difficult to accurately interpret chromosomal correspondences such as true orthology and paralogy due to significant divergence of genomes from a common ancestor...