Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Search-based graph queries, such as finding short paths and isomorphic subgraphs, are dominated by memory latency. If input graphs can be partitioned appropriately, large cluster...
Jonathan W. Berry, Bruce Hendrickson, Simon Kahan,...
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Background: The identification of species or species groups with specific oligo-nucleotides as molecular signatures is becoming increasingly popular for bacterial samples. However...
Biological networks are commonly used to model molecular activity within the cell. Recent experimental studies have shown that the detection of conserved subnetworks across several...