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» A Structure-Based Flexible Search Method for Motifs in RNA
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BMCBI
2006
116views more  BMCBI 2006»
14 years 10 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
BMCBI
2006
91views more  BMCBI 2006»
14 years 10 months ago
In silico identification of putative promoter motifs of White Spot Syndrome Virus
Background: White Spot Syndrome Virus, a member of the virus family Nimaviridae, is a large dsDNA virus infecting shrimp and other crustacean species. Although limited information...
Hendrik Marks, Xin-Ying Ren, Hans Sandbrink, Mari&...
JCB
2008
159views more  JCB 2008»
14 years 10 months ago
BayesMD: Flexible Biological Modeling for Motif Discovery
We present BayesMD, a Bayesian Motif Discovery model with several new features. Three different types of biological a priori knowledge are built into the framework in a modular fa...
Man-Hung Eric Tang, Anders Krogh, Ole Winther
ALMOB
2006
155views more  ALMOB 2006»
14 years 10 months ago
Refining motifs by improving information content scores using neighborhood profile search
The main goal of the motif finding problem is to detect novel, over-represented unknown signals in a set of sequences (e.g. transcription factor binding sites in a genome). The mo...
Chandan K. Reddy, Yao-Chung Weng, Hsiao-Dong Chian...
BMCBI
2008
128views more  BMCBI 2008»
14 years 10 months ago
SIGffRid: A tool to search for sigma factor binding sites in bacterial genomes using comparative approach and biologically drive
Background: Many programs have been developed to identify transcription factor binding sites. However, most of them are not able to infer two-word motifs with variable spacer leng...
Fabrice Touzain, Sophie Schbath, Isabelle Debled-R...