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BMCBI
2008
168views more  BMCBI 2008»
14 years 10 months ago
Predicting protein folding pathways at the mesoscopic level based on native interactions between secondary structure elements
Background: Since experimental determination of protein folding pathways remains difficult, computational techniques are often used to simulate protein folding. Most current techn...
Qingwu Yang, Sing-Hoi Sze
BMCBI
2008
136views more  BMCBI 2008»
14 years 10 months ago
An efficient method for the prediction of deleterious multiple-point mutations in the secondary structure of RNAs using suboptim
Background: RNAmute is an interactive Java application which, given an RNA sequence, calculates the secondary structure of all single point mutations and organizes them into categ...
Alexander Churkin, Danny Barash
AE
2005
Springer
15 years 3 months ago
Incorporating Knowledge of Secondary Structures in a L-System-Based Encoding for Protein Folding
An encoding scheme for protein folding on lattice models, inspired by parametric L-systems, was proposed. The encoding incorporates problem domain knowledge in the form of predesig...
Gabriela Ochoa, Gabi Escuela, Natalio Krasnogor
GCB
2010
Springer
145views Biometrics» more  GCB 2010»
14 years 8 months ago
Shape-based Barrier Estimation for RNAs
: The ability of some RNA molecules to switch between different metastable conformations plays an important role in cellular processes. In order to identify such molecules and to p...
Sergiy Bogomolov, Martin Mann, Björn Voß...
EDBT
2012
ACM
257views Database» more  EDBT 2012»
13 years 15 days ago
Indexing and mining topological patterns for drug discovery
Increased availability of large repositories of chemical compounds has created new challenges and opportunities for the application of data-mining and indexing techniques to probl...
Sayan Ranu, Ambuj K. Singh