Peptide compositions constructed out of whole sets of protein sequences can be used as species signatures for phylogenetic analysis. To account for point mutations, an amino acid ...
Hidden Markov Models are a widely used generative model for analysing sequence data. A variant, Profile Hidden Markov Models are a special case used in Bioinformatics to represent,...
Stefan Mutter, Bernhard Pfahringer, Geoffrey Holme...
Background: The functions of human cells are carried out by biomolecular networks, which include proteins, genes, and regulatory sites within DNA that encode and control protein e...
We show that traditional waveform-coding and 3-D modelbased coding are not competing alternatives but should be combined to support and complement each other. Both approaches are ...
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...