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BMCBI
2010
160views more  BMCBI 2010»
14 years 10 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian
BMCBI
2007
130views more  BMCBI 2007»
14 years 10 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
ISBI
2002
IEEE
15 years 10 months ago
Automated determination of protein subcellular locations from 3D fluorescence microscope images
Knowing the subcellular location of a protein is critical to a full understanding of its function, and automated, objective methods for assigning locations are needed as part of t...
Meel Velliste, Robert F. Murphy
CLEIEJ
2007
152views more  CLEIEJ 2007»
14 years 10 months ago
Gene Expression Analysis using Markov Chains extracted from RNNs
Abstract. This paper present a new approach for the analysis of gene expression, by extracting a Markov Chain from trained Recurrent Neural Networks (RNNs). A lot of microarray dat...
Igor Lorenzato Almeida, Denise Regina Pechmann Sim...
BMCBI
2007
117views more  BMCBI 2007»
14 years 10 months ago
Meta-analysis of several gene lists for distinct types of cancer: A simple way to reveal common prognostic markers
Background: Although prognostic biomarkers specific for particular cancers have been discovered, microarray analysis of gene expression profiles, supported by integrative analysis...
Xinan Yang, Xiao Sun