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» Analysis of variance components in gene expression data
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BMCBI
2006
173views more  BMCBI 2006»
14 years 9 months ago
Kernel-based distance metric learning for microarray data classification
Background: The most fundamental task using gene expression data in clinical oncology is to classify tissue samples according to their gene expression levels. Compared with tradit...
Huilin Xiong, Xue-wen Chen
BMCBI
2005
89views more  BMCBI 2005»
14 years 9 months ago
Comparative analysis of chromatin landscape in regulatory regions of human housekeeping and tissue specific genes
Background: Global regulatory mechanisms involving chromatin assembly and remodelling in the promoter regions of genes is implicated in eukaryotic transcription control especially...
Mythily Ganapathi, Pragya Srivastava, Sushanta Kum...
BMCBI
2010
178views more  BMCBI 2010»
14 years 10 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...
BMCBI
2006
100views more  BMCBI 2006»
14 years 9 months ago
Chromosomal patterns of gene expression from microarray data: methodology, validation and clinical relevance in gliomas
Background: Expression microarrays represent a powerful technique for the simultaneous investigation of thousands of genes. The evidence that genes are not randomly distributed in...
Federico E. Turkheimer, Federico Roncaroli, Benoit...
TSMC
2008
136views more  TSMC 2008»
14 years 9 months ago
Learning Relational Descriptions of Differentially Expressed Gene Groups
Abstract-- This paper presents a method that uses gene ontologies, together with the paradigm of relational subgroup discovery, to find compactly described groups of genes differen...
Igor Trajkovski, Filip Zelezný, Nada Lavrac...