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» Approximating the Number of Network Motifs
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ALMOB
2006
138views more  ALMOB 2006»
14 years 11 months ago
A combinatorial optimization approach for diverse motif finding applications
Background: Discovering approximately repeated patterns, or motifs, in biological sequences is an important and widely-studied problem in computational molecular biology. Most fre...
Elena Zaslavsky, Mona Singh
WABI
2010
Springer
167views Bioinformatics» more  WABI 2010»
14 years 10 months ago
Quantifying the Strength of Natural Selection of a Motif Sequence
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
Chen-Hsiang Yeang
KDD
1997
ACM
161views Data Mining» more  KDD 1997»
15 years 3 months ago
Automated Discovery of Active Motifs in Three Dimensional Molecules
In this paper 1 we present a method for discovering approximately common motifs (also known as active motifs) in three dimensional (3D) molecules. Each node in a molecule is repre...
Xiong Wang, Jason Tsong-Li Wang, Dennis Shasha, Br...
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ICDM
2009
IEEE
121views Data Mining» more  ICDM 2009»
15 years 6 months ago
Finding Time Series Motifs in Disk-Resident Data
—Time series motifs are sets of very similar subsequences of a long time series. They are of interest in their own right, and are also used as inputs in several higher-level data...
Abdullah Mueen, Eamonn J. Keogh, Nima Bigdely Sham...
BMCBI
2004
111views more  BMCBI 2004»
14 years 11 months ago
Aggregation of topological motifs in the Escherichia coli transcriptional regulatory network
Background: Transcriptional regulation of cellular functions is carried out through a complex network of interactions among transcription factors and the promoter regions of genes...
Radu Dobrin, Qasim K. Beg, Albert-Lászl&oac...