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» Bayesian Protein Family Classifier
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BMCBI
2010
134views more  BMCBI 2010»
14 years 11 months ago
BayesMotif: de novo protein sorting motif discovery from impure datasets
Background: Protein sorting is the process that newly synthesized proteins are transported to their target locations within or outside of the cell. This process is precisely regul...
Jianjun Hu, Fan Zhang
BMCBI
2008
143views more  BMCBI 2008»
14 years 11 months ago
Gene identification and protein classification in microbial metagenomic sequence data via incremental clustering
Background: The identification and study of proteins from metagenomic datasets can shed light on the roles and interactions of the source organisms in their communities. However, ...
Shibu Yooseph, Weizhong Li, Granger G. Sutton
NAR
2002
164views more  NAR 2002»
14 years 11 months ago
SCOP database in 2002: refinements accommodate structural genomics
The SCOP (Structural Classification of Proteins) database is a comprehensive ordering of all proteins of known structure, according to their evolutionary and structural relationsh...
Loredana Lo Conte, Steven E. Brenner, Tim J. P. Hu...
JCB
2002
74views more  JCB 2002»
14 years 11 months ago
Using Substitution Matrices to Estimate Probability Distributions for Biological Sequences
Accurately estimating probabilities from observations is important for probabilistic-based approaches to problems in computational biology. In this paper we present a biologically...
Eleazar Eskin, William Stafford Noble, Yoram Singe...
BMCBI
2004
101views more  BMCBI 2004»
14 years 11 months ago
A database for G proteins and their interaction with GPCRs
Background: G protein-coupled receptors (GPCRs) transduce signals from extracellular space into the cell, through their interaction with G proteins, which act as switches forming ...
Antigoni L. Elefsinioti, Pantelis G. Bagos, Ioanni...