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BMCBI
2008
162views more  BMCBI 2008»
14 years 10 months ago
Background correction using dinucleotide affinities improves the performance of GCRMA
Background: High-density short oligonucleotide microarrays are a primary research tool for assessing global gene expression. Background noise on microarrays comprises a significan...
Raad Z. Gharaibeh, Anthony Fodor, Cynthia Gibas
BMCBI
2008
170views more  BMCBI 2008»
14 years 10 months ago
A genetic approach for building different alphabets for peptide and protein classification
Background: In this paper, it is proposed an optimization approach for producing reduced alphabets for peptide classification, using a Genetic Algorithm. The classification task i...
Loris Nanni, Alessandra Lumini
BMCBI
2008
94views more  BMCBI 2008»
14 years 10 months ago
Structural assembly of two-domain proteins by rigid-body docking
Background: Modelling proteins with multiple domains is one of the central challenges in Structural Biology. Although homology modelling has successfully been applied for predicti...
Tammy M. K. Cheng, Tom L. Blundell, Juan Fern&aacu...
CORR
2010
Springer
119views Education» more  CORR 2010»
14 years 10 months ago
Report on the XBase Project
This project addressed the conceptual fundamentals of data storage, investigating techniques for provision of highly generic storage facilities that can be tailored to produce var...
Evangelos Zirintsis, Graham N. C. Kirby, Alan Dear...
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ALMOB
2006
155views more  ALMOB 2006»
14 years 10 months ago
Refining motifs by improving information content scores using neighborhood profile search
The main goal of the motif finding problem is to detect novel, over-represented unknown signals in a set of sequences (e.g. transcription factor binding sites in a genome). The mo...
Chandan K. Reddy, Yao-Chung Weng, Hsiao-Dong Chian...