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CSB
2005
IEEE
152views Bioinformatics» more  CSB 2005»
15 years 9 months ago
Consensus Genetic Maps: A Graph Theoretic Approach
A genetic map is an ordering of genetic markers constructed from genetic linkage data for use in linkage studies and experimental design. While traditional methods have focused on...
Benjamin G. Jackson, Srinivas Aluru, Patrick S. Sc...
CSB
2005
IEEE
125views Bioinformatics» more  CSB 2005»
15 years 9 months ago
Discriminative Discovery of Transcription Factor Binding Sites from Location Data
Motivation: The availability of genome-wide location analyses based on chromatin immunoprecipitation (ChIP) data gives a new insight for in silico analysis of transcriptional regu...
Yuji Kawada, Yasubumi Sakakibara
CSB
2005
IEEE
135views Bioinformatics» more  CSB 2005»
15 years 9 months ago
Relating transcription factors, modules of genes and cultivation conditions in Saccharomyces cerevisiae
Usually, the functionality of a module of co-expressed genes is derived from enrichment within the module of a particular gene annotation category. The systematic setup of the che...
Theo A. Knijnenburg, Marcel J. T. Reinders, J. M. ...
CSB
2005
IEEE
135views Bioinformatics» more  CSB 2005»
15 years 9 months ago
Inverse Design of Large Molecules using Linear Diophantine Equations
We have previously developed a method [1] for the inverse design of small ligands. This method can be used to design novel compounds with optimized properties (such as drugs) and ...
Shawn Martin, W. Michael Brown, Jean-Loup Faulon, ...
CSB
2005
IEEE
137views Bioinformatics» more  CSB 2005»
15 years 9 months ago
A Learned Comparative Expression Measure for Affymetrix GeneChip DNA Microarrays
Perhaps the most common question that a microarray study can ask is, “Between two given biological conditions, which genes exhibit changed expression levels?” Existing methods...
Will Sheffler, Eli Upfal, John Sedivy, William Sta...