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148
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CBMS
2001
IEEE
15 years 7 months ago
An Interoperable Data Architecture for Data Exchange in a Biomedical Research Network
Knowledge discovery and data correlation require a unified approach to basic data management. However, achieving such an approach is nearly impossible with hundreds of disparate d...
Daniel J. Crichton, J. Steven Hughes, Gregory J. D...
136
Voted
BIRD
2008
Springer
162views Bioinformatics» more  BIRD 2008»
15 years 5 months ago
Suffix Tree Characterization of Maximal Motifs in Biological Sequences
Finding motifs in biological sequences is one of the most intriguing problems for string algorithms designers due to, on the one hand, the numerous applications of this problem in...
Maria Federico, Nadia Pisanti
126
Voted
BIRD
2008
Springer
141views Bioinformatics» more  BIRD 2008»
15 years 5 months ago
Nested q-Partial Graphs for Genetic Network Inference from "Small n, Large p" Microarray Data
Abstract. Gaussian graphical models are widely used to tackle the important and challenging problem of inferring genetic regulatory networks from expression data. These models have...
Kevin Kontos, Gianluca Bontempi
BIRD
2008
Springer
109views Bioinformatics» more  BIRD 2008»
15 years 5 months ago
A Robust Class of Stable Proteins in the 2D HPC Model
The inverse protein folding problem is that of designing an amino acid sequence which has a prescribed native protein fold. This problem arises in drug design where a particular st...
Alireza Hadj Khodabakhshi, Ján Manuch, Aras...
113
Voted
DNA
2008
Springer
15 years 5 months ago
A Simple DNA Gate Motif for Synthesizing Large-Scale Circuits
The prospects of programming molecular systems to perform complex autonomous tasks has motivated research into the design of synthetic biochemical circuits. Of particular interest ...
Lulu Qian, Erik Winfree