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» Challenges for knowledge discovery in biology
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BMCBI
2010
95views more  BMCBI 2010»
14 years 9 months ago
Quantifying the relationship between sequence and three-dimensional structure conservation in RNA
Background: In recent years, the number of available RNA structures has rapidly grown reflecting the increased interest on RNA biology. Similarly to the studies carried out two de...
Emidio Capriotti, Marc A. Martí-Renom
BMCBI
2004
169views more  BMCBI 2004»
14 years 9 months ago
A power law global error model for the identification of differentially expressed genes in microarray data
Background: High-density oligonucleotide microarray technology enables the discovery of genes that are transcriptionally modulated in different biological samples due to physiolog...
Norman Pavelka, Mattia Pelizzola, Caterina Vizzard...
72
Voted
FGCS
2007
106views more  FGCS 2007»
14 years 9 months ago
Distributed data mining services leveraging WSRF
The continuous increase of data volumes available from many sources raises new challenges for their effective understanding. Knowledge discovery in large data repositories involv...
Antonio Congiusta, Domenico Talia, Paolo Trunfio
86
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SAC
2009
ACM
15 years 4 months ago
A new protein motif extraction framework based on constrained co-clustering
Signal finding (pattern discovery) in biological sequences is a fundamental problem in both computer science and molecular biology. Many approaches have been proposed for extract...
Francesca Cordero, Alessia Visconti, Marco Botta
WWW
2006
ACM
15 years 10 months ago
Knowledge modeling and its application in life sciences: a tale of two ontologies
High throughput glycoproteomics, similar to genomics and proteomics, involves extremely large volumes of distributed, heterogeneous data as a basis for identification and quantifi...
Satya Sanket Sahoo, Christopher Thomas, Amit P. Sh...