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» Challenges for knowledge discovery in biology
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107
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BMCBI
2010
178views more  BMCBI 2010»
15 years 18 days ago
CNV Workshop: an integrated platform for high-throughput copy number variation discovery and clinical diagnostics
Background: Recent studies have shown that copy number variations (CNVs) are frequent in higher eukaryotes and associated with a substantial portion of inherited and acquired risk...
Xiaowu Gai, Juan C. Perin, Kevin Murphy, Ryan O'Ha...
172
Voted
RECOMB
2001
Springer
16 years 24 days ago
Finding motifs using random projections
motif discovery problem abstracts the task of discovering short, conserved sites in genomic DNA. Pevzner and Sze recently described a precise combinatorial formulation of motif di...
Jeremy Buhler, Martin Tompa
94
Voted
GECCO
2005
Springer
140views Optimization» more  GECCO 2005»
15 years 6 months ago
MDGA: motif discovery using a genetic algorithm
Computationally identifying transcription factor binding sites in the promoter regions of genes is an important problem in computational biology and has been under intensive resea...
Dongsheng Che, Yinglei Song, Khaled Rasheed
118
Voted
BMCBI
2011
14 years 4 months ago
Biomarker Discovery and Redundancy Reduction towards Classification using a Multi-factorial MALDI-TOF MS T2DM Mouse Model Datase
Background: Diabetes like many diseases and biological processes is not mono-causal. On the one hand multifactorial studies with complex experimental design are required for its c...
Chris Bauer, Frank Kleinjung, Celia J. Smith, Mark...
127
Voted
SIGIR
2008
ACM
15 years 12 days ago
Advances in information and knowledge management
Several research areas today overlap between the tracks of databases, information retrieval and knowledge management, such as natural language processing, semantic web, digital li...
Aparna S. Varde, Jian Pei