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BMCBI
2008
131views more  BMCBI 2008»
14 years 12 months ago
CoCoNUT: an efficient system for the comparison and analysis of genomes
Background: Comparative genomics is the analysis and comparison of genomes from different species. This area of research is driven by the large number of sequenced genomes and hea...
Mohamed Ibrahim Abouelhoda, Stefan Kurtz, Enno Ohl...
BMCBI
2006
137views more  BMCBI 2006»
14 years 12 months ago
Genome BLAST distance phylogenies inferred from whole plastid and whole mitochondrion genome sequences
Background: Phylogenetic methods which do not rely on multiple sequence alignments are important tools in inferring trees directly from completely sequenced genomes. Here, we exte...
Alexander F. Auch, Stefan R. Henz, Barbara R. Holl...
HIPC
2009
Springer
14 years 9 months ago
Comparing the performance of clusters, Hadoop, and Active Disks on microarray correlation computations
Abstract--Microarray-based comparative genomic hybridization (aCGH) offers an increasingly fine-grained method for detecting copy number variations in DNA. These copy number variat...
Jeffrey A. Delmerico, Nathanial A. Byrnes, Andrew ...
BMCBI
2011
14 years 6 months ago
Multithreaded comparative RNA secondary structure prediction using stochastic context-free grammars
Background: The prediction of the structure of large RNAs remains a particular challenge in bioinformatics, due to the computational complexity and low levels of accuracy of state...
Zsuzsanna Sukosd, Bjarne Knudsen, Morten Vaerum, J...
BMCBI
2011
14 years 3 months ago
Improving pan-genome annotation using whole genome multiple alignment
Background: Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology. Genome annotations c...
Samuel V. Angiuoli, Julie C. Dunning Hotopp, Steve...