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BMCBI
2010
214views more  BMCBI 2010»
15 years 1 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
KDD
2003
ACM
148views Data Mining» more  KDD 2003»
16 years 1 months ago
A highly-usable projected clustering algorithm for gene expression profiles
Projected clustering has become a hot research topic due to its ability to cluster high-dimensional data. However, most existing projected clustering algorithms depend on some cri...
Kevin Y. Yip, David W. Cheung, Michael K. Ng
BMCBI
2006
166views more  BMCBI 2006»
15 years 1 months ago
bioNMF: a versatile tool for non-negative matrix factorization in biology
Background: In the Bioinformatics field, a great deal of interest has been given to Non-negative matrix factorization technique (NMF), due to its capability of providing new insig...
Alberto D. Pascual-Montano, Pedro Carmona-Saez, Mo...
BIBE
2007
IEEE
155views Bioinformatics» more  BIBE 2007»
15 years 7 months ago
Partial Mixture Model for Tight Clustering in Exploratory Gene Expression Analysis
Abstract—In this paper we demonstrate the inherent robustness of minimum distance estimator that makes it a potentially powerful tool for parameter estimation in gene expression ...
Yinyin Yuan, Chang-Tsun Li
BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
15 years 1 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li