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» Clustering cancer gene expression data: a comparative study
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BMCBI
2008
135views more  BMCBI 2008»
14 years 12 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
BMCBI
2006
173views more  BMCBI 2006»
14 years 11 months ago
Kernel-based distance metric learning for microarray data classification
Background: The most fundamental task using gene expression data in clinical oncology is to classify tissue samples according to their gene expression levels. Compared with tradit...
Huilin Xiong, Xue-wen Chen
BMCBI
2007
157views more  BMCBI 2007»
14 years 12 months ago
Improving gene set analysis of microarray data by SAM-GS
Background: Gene-set analysis evaluates the expression of biological pathways, or a priori defined gene sets, rather than that of individual genes, in association with a binary ph...
Irina Dinu, John D. Potter, Thomas Mueller, Qi Liu...
BMCBI
2010
135views more  BMCBI 2010»
14 years 12 months ago
Detecting disease associated modules and prioritizing active genes based on high throughput data
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
Yu-Qing Qiu, Shi-Hua Zhang, Xiang-Sun Zhang, Luona...
VLDB
2004
ACM
143views Database» more  VLDB 2004»
15 years 5 months ago
GPX: Interactive Mining of Gene Expression Data
Discovering co-expressed genes and coherent expression patterns in gene expression data is an important data analysis task in bioinformatics research and biomedical applications. ...
Daxin Jiang, Jian Pei, Aidong Zhang