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IDA
2005
Springer
15 years 3 months ago
Biological Cluster Validity Indices Based on the Gene Ontology
With the invention of biotechnological high throughput methods like DNA microarrays and the analysis of the resulting huge amounts of biological data, clustering algorithms gain ne...
Nora Speer, Christian Spieth, Andreas Zell
BMCBI
2007
117views more  BMCBI 2007»
14 years 9 months ago
Meta-analysis of several gene lists for distinct types of cancer: A simple way to reveal common prognostic markers
Background: Although prognostic biomarkers specific for particular cancers have been discovered, microarray analysis of gene expression profiles, supported by integrative analysis...
Xinan Yang, Xiao Sun
BMCBI
2006
155views more  BMCBI 2006»
14 years 9 months ago
A powerful method for detecting differentially expressed genes from GeneChip arrays that does not require replicates
Background: Studies of differential expression that use Affymetrix GeneChip arrays are often carried out with a limited number of replicates. Reasons for this include financial co...
Anne-Mette K. Hein, Sylvia Richardson
BMCBI
2004
146views more  BMCBI 2004»
14 years 9 months ago
Multivariate search for differentially expressed gene combinations
Background: To identify differentially expressed genes, it is standard practice to test a twosample hypothesis for each gene with a proper adjustment for multiple testing. Such te...
Yuanhui Xiao, Robert D. Frisina, Alexander Gordon,...
BIOINFORMATICS
2005
151views more  BIOINFORMATICS 2005»
14 years 9 months ago
Differential and trajectory methods for time course gene expression data
Motivation: The issue of high dimensionality in microarray data has been, and remains, a hot topic in statistical and computational analysis. Efficient gene filtering and differen...
Yulan Liang, Bamidele Tayo, Xueya Cai, Arpad Kelem...