With the invention of biotechnological high throughput methods like DNA microarrays and the analysis of the resulting huge amounts of biological data, clustering algorithms gain ne...
Background: Although prognostic biomarkers specific for particular cancers have been discovered, microarray analysis of gene expression profiles, supported by integrative analysis...
Background: Studies of differential expression that use Affymetrix GeneChip arrays are often carried out with a limited number of replicates. Reasons for this include financial co...
Background: To identify differentially expressed genes, it is standard practice to test a twosample hypothesis for each gene with a proper adjustment for multiple testing. Such te...
Yuanhui Xiao, Robert D. Frisina, Alexander Gordon,...
Motivation: The issue of high dimensionality in microarray data has been, and remains, a hot topic in statistical and computational analysis. Efficient gene filtering and differen...