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IMSCCS
2006
IEEE
15 years 3 months ago
Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...
Linyong Mao, W. Jim Zheng
RECOMB
2007
Springer
15 years 9 months ago
Multi-break Rearrangements: From Circular to Linear Genomes
Multi-break rearrangements break a genome into multiple fragments and further glue them together in a new order. While 2break rearrangements represent standard reversals, fusions, ...
Max A. Alekseyev
CANDC
2005
ACM
14 years 9 months ago
Haplotype assembly from aligned weighted SNP fragments
Given an assembled genome of a diploid organism the haplotype assembly problem can be formulated as retrieval of a pair of haplotypes from a set of aligned weighted SNP fragments....
Yu-Ying Zhao, Ling-Yun Wu, Ji-Hong Zhang, Rui-Shen...
JIB
2007
89views more  JIB 2007»
14 years 9 months ago
A Methodology for Comparative Functional Genomics
The continuing and rapid increase in the number of fully sequenced genomes is creating new opportunities for comparative studies. However, although many genomic databases store da...
Intikhab Alam, Mike Cornell, Darren M. Soanes, Cor...
BIOINFORMATICS
2008
203views more  BIOINFORMATICS 2008»
14 years 9 months ago
The SGN comparative map viewer
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
Lukas A. Mueller, Adri A. Mills, Beth Skwarecki, R...