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» Comparative genome assembly
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94
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BMCBI
2007
124views more  BMCBI 2007»
15 years 20 days ago
CRISPR Recognition Tool (CRT): a tool for automatic detection of clustered regularly interspaced palindromic repeats
Background: Clustered Regularly Interspaced Palindromic Repeats (CRISPRs) are a novel type of direct repeat found in a wide range of bacteria and archaea. CRISPRs are beginning to...
Charles Bland, Teresa L. Ramsey, Fareedah Sabree, ...
BMCBI
2007
181views more  BMCBI 2007»
15 years 24 days ago
ASMPKS: an analysis system for modular polyketide synthases
Background: Polyketides are secondary metabolites of microorganisms with diverse biological activities, including pharmacological functions such as antibiotic, antitumor and agroc...
Hongseok Tae, Eun-Bae Kong, Kiejung Park
103
Voted
BMCBI
2010
127views more  BMCBI 2010»
15 years 24 days ago
Deriving enzymatic and taxonomic signatures of metagenomes from short read data
Background: We propose a method for deriving enzymatic signatures from short read metagenomic data of unknown species. The short read data are converted to six pseudo-peptide cand...
Uri Weingart, Erez Persi, Uri Gophna, David Horn
115
Voted
BMCBI
2006
123views more  BMCBI 2006»
15 years 22 days ago
An Automated Method for Rapid Identification of Putative Gene Family Members in Plants
Background: Gene duplication events have played a significant role in genome evolution, particularly in plants. Exhaustive searches for all members of a known gene family as well ...
Ronald L. Frank, Ajay Mane, Fikret Erçal
116
Voted
BMCBI
2006
142views more  BMCBI 2006»
15 years 22 days ago
Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with
Background: Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several ...
Angela Re, Davide Corà, Alda Maria Puliti, ...