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» Comparative modeling without implicit sequence alignments
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BIOINFORMATICS
2007
52views more  BIOINFORMATICS 2007»
15 years 23 days ago
Comparative modeling without implicit sequence alignments
Andrzej Kolinski, Dominik Gront
89
Voted
BMCBI
2007
115views more  BMCBI 2007»
15 years 23 days ago
Comparing sequences without using alignments: application to HIV/SIV subtyping
Background: In general, the construction of trees is based on sequence alignments. This procedure, however, leads to loss of informationwhen parts of sequence alignments (for inst...
Gilles Didier, Laurent Debomy, Maude Pupin, Ming Z...
97
Voted
CSB
2003
IEEE
110views Bioinformatics» more  CSB 2003»
15 years 6 months ago
Prokaryote Phylogeny without Sequence Alignment: From Avoidance Signature to Composition Distance
A new and essentially simple method to reconstruct prokaryotic phylogenetic trees from their complete genome data without using sequence alignment is proposed. It is based on the ...
Bailin Hao, Ji Qi
130
Voted
BMCBI
2007
142views more  BMCBI 2007»
15 years 20 days ago
Predicting and improving the protein sequence alignment quality by support vector regression
Background: For successful protein structure prediction by comparative modeling, in addition to identifying a good template protein with known structure, obtaining an accurate seq...
Minho Lee, Chan-seok Jeong, Dongsup Kim
111
Voted
BMCBI
2010
133views more  BMCBI 2010»
15 years 23 days ago
Improving de novo sequence assembly using machine learning and comparative genomics for overlap correction
Background: With the rapid expansion of DNA sequencing databases, it is now feasible to identify relevant information from prior sequencing projects and completed genomes and appl...
Lance E. Palmer, Mathäus Dejori, Randall A. B...