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BMCBI
2005
152views more  BMCBI 2005»
14 years 9 months ago
GeneKeyDB: A lightweight, gene-centric, relational database to support data mining environments
Background: The analysis of biological data is greatly enhanced by existing or emerging databases. Most existing databases, with few exceptions are not designed to easily support ...
S. A. Kirov, X. Peng, E. Baker, D. Schmoyer, B. Zh...
IPPS
2006
IEEE
15 years 3 months ago
Parallel implementation of the replica exchange molecular dynamics algorithm on Blue Gene/L
The Replica Exchange method is a popular approach for studying the folding thermodynamics of small to modest size proteins in explicit solvent, since it is easily parallelized. Ho...
Maria Eleftheriou, Aleksandr Rayshubskiy, Jed W. P...
BIOCOMP
2006
14 years 11 months ago
Dynamic Bayesian Network (DBN) with Structure Expectation Maximization (SEM) for Modeling of Gene Network from Time Series Gene
Exploring gene regulatory network is a key topic in molecular biology. In this paper, we present a new dynamic Bayesian network (DBN) framework embedded with structural expectatio...
Yu Zhang, Zhidong Deng, Hongshan Jiang, Peifa Jia
BMCBI
2006
142views more  BMCBI 2006»
14 years 9 months ago
Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with
Background: Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several ...
Angela Re, Davide Corà, Alda Maria Puliti, ...
BMCBI
2002
134views more  BMCBI 2002»
14 years 9 months ago
CoreGenes: A computational tool for identifying and cataloging "core" genes in a set of small genomes
Background: Improvements in DNA sequencing technology and methodology have led to the rapid expansion of databases comprising DNA sequence, gene and genome data. Lower operational...
Nikhat Zafar, Raja Mazumder, Donald Seto