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TCS
2010
14 years 8 months ago
Computing the graph-based parallel complexity of gene assembly
We consider a graph-theoretical formalization of the process of gene assembly in ciliates introduced in Ehrenfeucht et al (2003), where a gene is modeled as a signed graph. The ge...
Artiom Alhazov, Chang Li, Ion Petre
BMCBI
2007
155views more  BMCBI 2007»
14 years 9 months ago
Current approaches to gene regulatory network modelling
Many different approaches have been developed to model and simulate gene regulatory networks. We proposed the following categories for gene regulatory network models: network part...
Thomas Schlitt, Alvis Brazma
BMCBI
2006
203views more  BMCBI 2006»
14 years 10 months ago
Genome-wide prediction of transcriptional regulatory elements of human promoters using gene expression and promoter analysis dat
Background: A complete understanding of the regulatory mechanisms of gene expression is the next important issue of genomics. Many bioinformaticians have developed methods and alg...
Seon-Young Kim, YongSung Kim
BMCBI
2010
160views more  BMCBI 2010»
14 years 10 months ago
Extracting consistent knowledge from highly inconsistent cancer gene data sources
Background: Hundreds of genes that are causally implicated in oncogenesis have been found and collected in various databases. For efficient application of these abundant but diver...
Xue Gong, Ruihong Wu, Yuannv Zhang, Wenyuan Zhao, ...
RECOMB
2002
Springer
15 years 10 months ago
Tests for gene clustering
Comparing chromosomal gene order in two or more related species is an important approach to studying the forces that guide genome organization and evolution. Linked clusters of si...
Dannie Durand, David Sankoff