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BMCBI
2005
109views more  BMCBI 2005»
14 years 11 months ago
Genome comparison without alignment using shortest unique substrings
Background: Sequence comparison by alignment is a fundamental tool of molecular biology. In this paper we show how a number of sequence comparison tasks, including the detection o...
Bernhard Haubold, Nora Pierstorff, Friedrich M&oum...
BIBE
2006
IEEE
139views Bioinformatics» more  BIBE 2006»
15 years 5 months ago
A Computational Inference Framework for analyzing Gene Regulation Pathway using Microarray Data
Microarray experiments produce gene expression data at such a high speed and volume that it is imperative to use highly specialized computational tools for their analyses. One grou...
Dong-Guk Shin, John Bluis, Yoo Ah Kim, Winfried Kr...
ALMOB
2006
155views more  ALMOB 2006»
14 years 11 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
GECCO
2005
Springer
124views Optimization» more  GECCO 2005»
15 years 5 months ago
The evolutionary computation approach to motif discovery in biological sequences
Finding motifs — patterns of conserved residues — within nucleotide and protein sequences is a key part of understanding function and regulation within biological systems. Thi...
Michael A. Lones, Andrew M. Tyrrell
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BMCBI
2007
79views more  BMCBI 2007»
14 years 11 months ago
Genomic scale analysis of lateral gene transfer in Apicomplexan parasites: insights into early eukaryotic evolution, host-pathog
ent> <title> <p>Highlights from the Third International Society for Computational Biology (ISCB) Student Council Symposium at the Fifteenth Annual International Conf...
Lucia Peixoto, David S. Roos