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BMCBI
2007
164views more  BMCBI 2007»
14 years 11 months ago
Comparison of probabilistic Boolean network and dynamic Bayesian network approaches for inferring gene regulatory networks
Background: The regulation of gene expression is achieved through gene regulatory networks (GRNs) in which collections of genes interact with one another and other substances in a...
Peng Li, Chaoyang Zhang, Edward J. Perkins, Ping G...
BIOINFORMATICS
2005
96views more  BIOINFORMATICS 2005»
14 years 11 months ago
BioLingua: a programmable knowledge environment for biologists
BioLingua is an interactive, web-based programming environment that enables biologists to analyze biological systems by combining knowledge and data through direct end-user progra...
J. P. Massar, Michael Travers, Jeff Elhai, Jeff Sh...
BMCBI
2010
153views more  BMCBI 2010»
14 years 12 months ago
GOAL: A software tool for assessing biological significance of genes groups
Background: Modern high throughput experimental techniques such as DNA microarrays often result in large lists of genes. Computational biology tools such as clustering are then us...
Alain B. Tchagang, Alexander Gawronski, Hugo B&eac...
IMSCCS
2006
IEEE
15 years 5 months ago
Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...
Linyong Mao, W. Jim Zheng
BMCBI
2006
121views more  BMCBI 2006»
14 years 12 months ago
Robust computational reconstitution - a new method for the comparative analysis of gene expression in tissues and isolated cell
Background: Biological tissues consist of various cell types that differentially contribute to physiological and pathophysiological processes. Determining and analyzing cell type-...
Martin Hoffmann, Dirk Pohlers, Dirk Koczan, Hans-J...